IXTAL is a research-driven company that provides solutions in the field of protein science and structural biology.
IXTAL offers discovery services for the production and purification of target proteins, their biochemical and biophysical characterisation.
Cloning strategies
Heterologous expression of proteins
Recombinant protein production
Protein chromatography purification
Biochemical and biophysical characterisation
Electrophoretic analysis
Protein-protein and protein-ligand interaction studies
Random mutagenesis
Site-directed mutagenesis
Chimeric proteins
Desole, C. et al. Engineering, characterization, and biological evaluation of an antibody targeting the HGF receptor Frontiers in Immunology, 2021 View at Publisher
Merlo, R. et al. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate Frontiers in Immunology, 2021, 36:85-97 View at Publisher
Ferrario, E. et al. Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline Acta Crystallographica, 2020, D76:496-505. View at Publisher
Ferraris, D.M. et al. Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form Biochemical and Biophysical Research Communications, 2019, 516(1):189-195. View at Publisher
Rossi, F. et al. Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe Biochemical and Biophysical Research Communications, 2018, 500(3):698-703. View at Publisher
Sarno, S. et al. Absolute structure and structure-function relationships of 4R,2′R and 4S,2′S Pidotimod® Journal of Molecular Structure, 2017, 1147:810-814. View at Publisher