IXTAL is a research-driven company that provides solutions in the field of protein science, structural biology and drug design.
IXTAL offers discovery services for the production and purification of target proteins, their biochemical and biophysical characterisation, and their X-ray structural analysis.
IXTAL services and expertise include in silico drug design, lead optimisation and small molecule X-ray diffraction for single crystal structure determination.
Heterologous expression of proteins
Recombinant protein production
Protein chromatography purification
Biochemical and biophysical characterisation
Protein-protein and protein-ligand interaction studies
Robot-assisted crystallization screening
X-ray data collection and analysis
Molecular docking simulation
Molecular dynamics simulation
Rossi, F. et al. Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe Biochemical and Biophysical Research Communications. Volume 500(3), 7 Jun 2018, Pages 698-703. View at Publisher
Sarno, S. et al. Absolute structure and structure-function relationships of 4R,2′R and 4S,2′S Pidotimod® Journal of Molecular Structure. Volume 1147, 5 November 2017, Pages 810-814. View at Publisher